Michael Marxen, Ph.D.

Group Leader Imaging Physics VCF

Michael Marxen

Contact information

Faculty of Medicine Carl Gustav Carus
Department of Psychiatry und Psychotherapy

Section of System Neuroscience
Würzburger Straße 35, 01187 Dresden

Phone: +49 (0)351 463-42212
E-Mail: michael.marxen@tu-dresden.de

Research Statement

My primary research interest are neuroimaging methods and their applications in the context of cognitive control, emotion regulation, and mental disorders. On the methods side, we employ functional and structural magnetic resonance imaging (MRI), electroencephalography (EEG) and other electrophysiological techniques and transcranial magnetic stimulation (TMS). A variety of software packages and statistical approaches are used to analyze the data. Current foci of our group are real-time, functional MRI (rt-fMRI) to generate neurofeedback and adapt stimulation paradigms, automated data processing workflows, diffusion tensor imaging and functional connectivity to study brain networks related to cognitive control, and arterial spin labeling in the context of pharmacological interventions.

Scientific Education

2004Ph.D.: Medical Biophysics, University of Toronto, Supervisor: Prof. R. M. Henkelman
1998Diploma: Physics, Ruprecht-Karls-Universität Heidelberg, Supervisor: B. Jähne 
1998 – 2004Graduate Studies: Department of Medical Biophysics, University of Toronto, Canada 
1993 – 1998Studies: Physics, Ruprecht-Karls-Universität Heidelberg
1994 – 1995Exchange Student: Physics, McMaster University, Hamilton, Canada
1991 – 1993Studies: Physics, Universität Osnabrück

Professional Experience

2015 - presentGroup Leader Imaging Physics, Department of Psychiatry and Neuroimaging Center, Technische Universität Dresden
2010 - 2014Technical Co-Director of the Neuroimaging Center (NIC) and MRI Research Physicist, Section of Systems Neuroscience, Technische Universität Dresden
Since 04/2010MR Research Physicist and Technical Co-Director Neuroimaging Centre, Department of Psychology, Technische Universität Dresden
12/2006 – 03/2010Postdoctoral Fellow, Rotman Research Institute, Baycrest, Toronto, Canada
06/2004 – 06/2005Research Associate, Sunnybrook & Women’s College Health Sciences Centre, Toronto, Canada
03/1998 – 08/1998Research Associate, University of Toronto, Department of Mechanical Engineering

Other Scientific Activities, Honors, Awards

2007University of Toronto – Edward Christie Stevens Fellowship ($5000)
2002 – 2003Government of Ontario – Ontario Graduate Scholarship (for Science & Technology)
1999 – 2002Heart and Stroke Foundation of Canada Graduate Scholarship
1994Ontario-Baden-Württemberg Student Exchange Scholarship

Selected Publications

M. Marxen, M. J. Jacob, D. K. Müller, L. Hellrung, S. Posse, P. Riedel, S. Bender, M. N. Smolka: Amygdala Regulation following fMRI-Neurofeedback without Instructed Strategies. Front. Human Neurosci. 2016; doi: 10.3389/fnhum.2016.00183

G. Gan, P. Sterzer, M. Marxen, U. S. Zimmermann, M. N. Smolka: Neural and Behavioral Correlates of Alcohol-Induced Aggression Under Provocation. Neuropsychopharmacology 2015; doi: 10.1038/npp.2015.141

S. Ehrlich, D. Geisler , F. Ritschel , J. A. King , M. Seidel, I. Schober, M. Breier, S. Clas, J. Weiss, M. Marxen, M. N. Smolka, V. Roessner, N. Kroemer: Elevated cognitive control over reward processing in recovered female patients with anorexia nervosa. J. Psychiatry Neurosci. 2015; 40(5):307-315

J. A. King, D. Geisler, F. Ritschel, I. Schober, M. Seidel, B. Roschinski, L. Soltwedel, J. Zwipp, G. Pfuhl, M. Marxen, V. Rössner, S. Ehrlich: Global cortical thinning in acute anorexia nervosa normalizes following long-term weight restoration. Biol. Psychiatry 2015; 77(7):624-632

M. Pilhatsch, N. C. Vetter, T. Hübner, S. Ripke, K. U. Müller, M. Marxen, S. Rodehacke, E. Mennigen, D. Schmidt, N. B. Kroemer, M. N. Smolka: Amygdala-function perturbations in healthy mid-adolescents with familial liability for depression. J. Am. Acad. Child Adolesc. Psychiatry 2014; 53(5):559-568

M. Muehlhan, M. Marxen, J. Landsiedel, H. Malberg, S. Zaunseder: The effect of body posture on cognitive performance: a question of sleep quality. Front. Hum. Neurosci. 2014; 8:171; doi: 10.3389/fnhum.2014.00171

G. Gan, A. Guevara, M. Marxen, M. Neumann, E. Jünger, A. Kobiella, E. Mennigen, M. Pilhatsch, D. Schwarz, U. S. Zimmermann, M. N. Smolka: Alcohol-induced impairment of inhibitory control is linked to attenuated brain responses in right fronto-temporal cortex. Biol. Psychiatry 2014; 76(9):698-707

M. Marxen, G. Gan, D. Schwarz, E. Mennigen, M. Pilhatsch, U. S. Zimmermann, M. Guenther, M. N. Smolka: Acute effects of alcohol on brain perfusion monitored with arterial spin labeling magnetic resonance imaging in young adults. J. Cereb. Blood Flow Metab. 2014; 34(3):472-479